Vaccinated roll-call

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Some data on vaccine effectiveness in reducing viral load of infected people, shortening the duration of symptoms, etc.

Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines | NEJM

Among participants with SARS-CoV-2 infection, the mean viral RNA load was 40% lower (95% CI, 16 to 57) in partially or fully vaccinated participants than in unvaccinated participants. In addition, the risk of febrile symptoms was 58% lower (relative risk, 0.42; 95% CI, 0.18 to 0.98) and the duration of illness was shorter, with 2.3 fewer days spent sick in bed (95% CI, 0.8 to 3.7).

Note the RNA viral load is not an accurate measure of how infectious you are, as RNA is not a measure of active live virus. However with less viral load the active virus will also be less.
 
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Pay wall - can you summarize...

Wildfire smoke - specifically the particulates in the smoke - may be affecting people's immune systems for the worse and appearing to cause an increase in COVID-19 cases.
 
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This is not working here.
Any further posts that are off topic from the original post title will be deleted.

Future discussions concerning public health, vaccination policy, dangers or efficacy, should be taken else where.
 
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Had my second dose of Astra Zeneca on Friday. No side of effects from either dose, not even a sore arm.

Not much chance of catching the virus here, hasn't been a case in the community for 15 months, but I love to travel, I have a 16 month old grand daughter in London whom I've never met and my bike's starting to feel neglected.
 
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Vaccinated back in March, 2 kids have mild cases now, but looks like vaccine works.
 
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This is not working here.
Any further posts that are off topic from the original post title will be deleted.

Future discussions concerning public health, vaccination policy, dangers or efficacy, should be taken else where.
Thank you.
 
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The murmurs are getting louder that it is going to be suggested to get a “booster dose” front line workers anyway. It always starts out as “strongly suggest” then “we are going to mandate” then if they get 75-80% of the place to go along they drop it. I’m fine I’ll go along but I’m going get that damn vertigo and miss days like I did the first two, unless I’m used to it now, that would be my preference.
My first full vaccination knocked me on my butt. I just received a booster and the side effects barely registered. One persons experience, I know, but thought I’d share.
 
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The murmurs are getting louder that it is going to be suggested to get a “booster dose” front line workers anyway. It always starts out as “strongly suggest” then “we are going to mandate” then if they get 75-80% of the place to go along they drop it. I’m fine I’ll go along but I’m going get that damn vertigo and miss days like I did the first two, unless I’m used to it now, that would be my preference.

I agree that a booster is ultimately likely for many people over the next year, especially given the differential efficacies of the various vaccines to the newer variants. In the long run, it wouldn't shock me if we needed COVID shots every year or two to keep up with mutations. Not so different than the flu vaccine.

How long did your vertigo last? I know that's not fun and a fairly rare side effect, so you were unlucky.

Not vaccine related, but my wife is prone to getting vertigo now and then (BPV). We can treat it at home by moving her head in a certain way (Epley maneuver) but she is miserable until we fix it.
Edited:
 
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I agree that a booster is ultimately likely for many people over the next year, especially given the differential efficacies of the various vaccines to the newer variants. In the long run, it wouldn't shock me if we needed COVID shots every year or two to keep up with mutations. Not so different than the flu vaccine.

How long did your vertigo last? I know that's not fun and a fairly rare side effect, so you were unlucky.

Not vaccine related, but my wife is prone to getting vertigo now and then (BPN). We can treat it at home by moving her head in a certain way (Epley maneuver) but she is miserable until we fix it.
Darn sucks your wife gotta deal with that it’s really freaky. I think the second dose that vertigo lasted “only” 3-4 days. But it set in right as the nurse pushed the plunger. I had gone to one of the drive through shot places for my second dose, I was getting nervous about my ability to drive home but it was good and wasn’t severe for several hours. I did have it one time prior to the vax so perhaps I’m genetically predisposed to it. Very unpleasant wouldn’t wish that on anyone. That was my only side effect, no flu or anything else, it was like being drunk without the fun part, I was stumbling around the house just waiting for it to pass. I have since run into a few people who had they same thing. They reported drinking a bunch of water really helped. That sounds way too simple to me but i will try it if these rumors are true.
 
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Not vaccine related, but my wife is prone to getting vertigo now and then (BPN). We can treat it at home by moving her head in a certain way (Epley maneuver) but she is miserable until we fix it.

If this is a recurrent problem, my patients have benefited from a reduction of salt and sugar in the diet (affects the fluid in the semi-circular canals), and importantly, checking for muscle spasms in the neck. With restricted cervical muscles, the eyes get conflicting information with neck rotation which can exacerbate the symptoms.
 
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Fully vaxxed with extra tracking chips in case one goes bad.
Moderna. Did have some side effects but totally beats landing in the ICU. Will be getting booster soon when authorized.
 
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We got our first jab yesterday and will get the second one in 4 weeks time. We would have got them sooner but until recently, Azerbaijan only had the Chinese vaccine which, as it stands, is not accepted as proof of vaccination in many countries. Now they offer the pzifer jab. Our only symptoms are a soar arm.
 
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My first full vaccination knocked me on my butt. I just received a booster and the side effects barely registered. One persons experience, I know, but thought I’d share.
Indonesian health workers got 3rd Moderna booster after 2 Sinovac jab. This is great news as Sinovac seems not too effective protecting against Delta variant.

2 of my brother in laws & 2 sister in laws got them 2 weeks ago. All reported more severe reaction compare to Sinovac, which include fever and headache. Most of symptoms gone after 3 days.

My son will receive it tomorrow. So he anticipated by taking high dose vitamin D and small dose paracetamol before the jab.
 
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Jabbed
1st - January
2nd February
3rd - August

How did the third dose go for you? I am immunocompromised and have a third dose scheduled for next week. All Pfizer for me. First two doses caused some fatigue and arm soreness, but nothing major.
 
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Just a quick update from Wife's COVID call today with the US Pentagon. They talk alot about the Military of course, which is sort of its own world so that data doesn't always jive well with the general population(mostly, but not always). So they also talk about CDC data and progress and then compare and contrast. One of the reasons why the information in so interesting. All data, no politics(least possible anyway).

One of the most interesting topics was about the ongoing effectiveness of the vaccines. Here in the US its primarily Moderna and Pfizer, which are both showing excellent staying power after 6months, with the 6 month mark being about 85%+ for any symptoms at all, and well over 90% against severe reactions (97% in some regions). The trouble is although it is real data, the data collection is not consistently collected nor always reliable depending on where it is collected, which is why the effectiveness is only an estimate and average. Still, its good enough to make a judgement on how good its working, which is great news.

So what is efficacy and effectiveness? These are terms which seem to be bandied about in the news quite interchangeably, and they should NOT be.

Here's the deal straight from the source(CDC):


More variables come into play in the real world, which is why it's so hard and time consuming to get new drugs and vaccines approved. There are several levels of clinical trials, all leading to broader test populations as safety is confirmed to a expected degree at each stage.

So because there are misunderstandings about what vaccine effectiveness really means, this may help:


And lastly a nice infographic on why herd immunity works, using the Delta variant as an example:



On a final note, please remember that 'cases' are just that, those that test positive for SARS-COV-2 virus. It does not mean COVID symptoms, or their severity, or risk of death. Just that the infection exists in a person, confirmed by test. Most people who contract the virus show no symptoms at all (as high as ~90%+).

The huge difference is between vaccinated and unvaccinated severity of symptoms if they present. CDC estimates, based on recent 2 week rolling data, death rate for vaccinated is ~1/100,000. For unvaccinated, ~1/50.

Compelling data, no doubt. Hope you find this interesting.
Edited:
 
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So I was vaccinated (both shots) in February, along with my inlaws. This past weekend my Father in law tested positive and has been feeling pretty cruddy. He's had life long asthma, and did end up going to the ER to get the monoclonal antibodies, but was soon discharged and sent home where he's been recuperating and taking a steroid too. My mother in law has not tested positive and has no symptoms. She will get re-tested again on Thursday.

For what it's worth, I live in Arizona.
 
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Just a quick update from Wife's COVID call today with the US Pentagon. They talk alot about the Military of course, which is sort of its own world so that data doesn't always jive well with the general population. Mostly, but not always, so they also talk about CDC data and progress and then compare and contrast. One of the reasons why the information in so interesting. All data, no politics(or least possible anyway).

One of the most interesting bits was about the ongoing effectiveness of the vaccines. Here in the US its primarily Moderna and Pfizer which are both showing excellent staying power after 6months, with the 6 month mark being about 85% or more for any symptoms at all, and well over 90% against severe reactions (97% in some regions). The trouble is although it is real data, the data collection is not consistently collected nor always reliable depending on where it is collected, which is why the effectiveness is only an estimate and average. Still, its good enough to make a judgement on how good its working, which is great news.

So the point I want to convey this time is regard to the terms efficacy and effectiveness, which seem to be bandied about in the news quite interchangeably, and it should NOT be.

Here's the deal straight from the source(CDC):


Many more variables come into play in the real world, which is why it's so hard and time consuming to get new drugs and vaccines approved. There are several levels of clinical trials, all leading to broader test populations as safety is confirmed to a expected degree at each stage.

So because there are misunderstandings about what vaccine effectiveness really means, this may help:


And lastly a nice infographic on why herd immunity works, using the Delta variant as an example:



On a final note, please remember that 'cases' are just that, those that test positive for SARS-COV-2 virus. It does not mean COVID symptoms, or their severity, or risk of death. Just that the infection exists in a person, confirmed by test. Most people who contract the virus show no symptoms at all (as high as ~90%).

The huge difference is between vaccinated and unvaccinated severity of symptoms if they present. CDC estimates, based on recent 2 week rolling data, death rate for vaccinated is ~1/100,000. For unvaccinated, ~1/50.

Compelling data, no doubt. Hope you find this interesting.
We had a vaccinated person test positive. Sent the place in a bit of an uproar but i talked to the MD and he stated “it very well could be he had a measurable amount of the virus in his nasal cavity and isn’t even infected.” Fortunately he was fine and had 0 symptoms. It spread to no one else even those unvaccinated. I would need to ask a lot more questions about having measurable amounts in ones nasal cavity and yet not be infected but I couldn’t get into it at the time and I’m afraid even if fully explained to me I’d have more questions about the whole testing process. Confusing stuff but I’m sure it makes perfect sense somewhere along the line.
 
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How did the third dose go for you? I am immunocompromised and have a third dose scheduled for next week. All Pfizer for me. First two doses caused some fatigue and arm soreness, but nothing major.

third vaccination received around 3 pm, post-vaccine symptoms fatigue/chill/possibly low grade fever next day 8 am, took tylenol and claritin, fall a sleep until 8 pm, next day no more symptoms. that was moderna vaccine. probably about same reaction as second dose.