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The applied U is also seen in late 50's chronos. The 227XX reference / range are late 50s early 60s ... Although the applied U maybe a little early for mid 50s, it is not wildly weird and within the realms of acceptable to see it on a 1.8 mill serial.
If you can find a 2270X with a serial before 200XXXX and applied U logo on the dial and does not look completely suss, ill eat my hat... 😉
227XXXX serial is early 63, from the date stampings inside 204612 and 20366 casebacks (marked by month/year).
(1963 ran serials from 227-231XXXX approximately).
Earliest serial i have recorded for any reference Polerouter with an applied U logo on the dial is 202XXXX, which should be 1960.
We should also consider that many medicos were in many cases, made to special order, so it is quite possible that the original watch may have started life as a uni-compax on a shop window and a change was requested at point of sale or later. That may explain the newer dial. Considering the fact that it is of the same era (less than five years apart), in my eyes I would find it quite acceptable.
To put it into context, it is not a 50's dial on a 40's watch but a very late 50's very early 60's dial on a late 50's case !