ConElPueblo
·It's all about the appearance from the front.
The screws at the back may or may not align due to the variances in screw threads.
Get the front ones all "right dressed" and the ones at the back will just keep it all tight, if not perfectly aligned.
It is very hard to align 8 or 10 fastening screws precisely and relatively to each other (it would probably require precise adjusting of each screw, or adding small shims behind the heads, and it would have to be done each time the case is opened; not great for toughness and WR). On most high end watches the screw heads on front are fake heads, they are hollow tubes/bolts easily aligned and the real fastening screws are on the other side where the misalignments are less obvious.
I know that is the case, hence my question. I can't name any watch with visible case screws that are aligned.

With a lot of force, and only once, I guess. 