That's either tempered mineral or sapphire. If the spot you refer to is dirt, I suspect it might be on the inside, or you probably would have cleaned it off by now. It it's on the inside, that's a colour of another horse. The case will need to be opened, and the movement removed. If the mark is a scratch, whether he crystal is tempered mineral or sapphire, you'd be best replacing it rather than trying to polish it out.
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