I would judge the situation at the time to see if the opportunity for a signature comes up, and only ask if it seems right in that setting. If thing seem okay to do so, asking for one would not be out of line, but I would not ask for more.
I've met a few celebrities and even made a commercial with one years ago, and during the shooting of the commercial I did ask for an autograph and photo together. I'm glad I asked as it does help reinforce the memory after the event.
Cheers, Al
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