The post industrial north is worse off with even less opportunity than they complained of so it hasn’t delivered anything.
the wealthy south is unhappy that the only thing that generated a decent tax surplus- financial services is outside any deal. In the long term if eu get their own capital markets going reliably ( and Germany had a few stumbles) , then the city is done for. Future innovation and reasonably effective regulation might allow the city to compete globally however at a time when everyone is looking at localisation and supply chain simplification this may not be easy. At least financial markets are often secondary to actual movement of goods where it seems likely paying a little more for local control may make sense.
Eu attitude to Russia, preventing spread of organised crime and fiscal control remain as serious issues for members.
For me It was a bad step overall and has made the U.K. watch world more insular in my view, but may reduce competition as others have said.