There is no reason that on a properly serviced movement that you can't leave the chrono running at all times.
If you consider the movement train from the mainspring to the escape wheel, those wheels/pinions and pivots are under torque from the mainspring at all times, and as long as the watch is running, which it does 24 hours a day, these parts are under stress.
Now compare the movement train to the chrono module, in the chrono module there is no stress being applied from the mainspring, only a rotational turning force is applied to the chono module wheels/pinions and pivots, and as long as they are clean and properly lubricated, there should not be any wear.
I just completed a servicing on this Cal 3220 movement, including of course complete teardown of the Dubois Duprez chrono module, and as proof of the light load on the pivots, only 9010 and 9020 oils are used throughout, the same oil for the 4th and escape and balance pivots on the base movement.
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